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Vilitra 40 mg (which contains vardenafil) should not be taken with nitroglycerin or any medications containing nitrates. Nitroglycerin is a medication commonly used to treat chest pain (angina) or heart conditions, and it belongs to a class of drugs called nitrates. Combining Vilitra 40 Mg with nitroglycerin or other nitrates can cause a sudden and severe drop in blood pressure, leading to dizziness, fainting, or even a heart attack. Both vardenafil, the active ingredient in Vilitra, and nitrates have vasodilatory effects, meaning they relax blood vessels and can cause a decrease in blood pressure. When taken together, these medications can potentiate each other's effects, resulting in dangerously low blood pressure levels. It's crucial to inform your healthcare provider about all medications you are taking, including prescription drugs, over-the-counter medications, supplements, and herbal products, to avoid potential interactions. If you are currently taking nitroglycerin or any other medication containing nitrates, it's essential to discuss this with your healthcare provider before using Vilitra 40 mg or any other medication for erectile dysfunction. If you experience chest pain or other symptoms of a heart attack while taking Vilitra 40 mg, seek immediate medical attention. Additionally, if you have any questions or concerns about the use of Vilitra 40 mg or its potential interactions with other medications, consult with your healthcare provider for personalized advice based on your individual health status and treatment needs.