- Posty: 166
- Dołączył(a): 26 lis 2022, o 07:18
25 maja 2024, o 11:15
Yes, Avana (avanafil) can interact with grapefruit or grapefruit juice. Grapefruit and grapefruit juice contain compounds that can interfere with the metabolism of certain medications, including avanafil. This interference can lead to increased levels of avanafil in the bloodstream, potentially increasing the risk of side effects.
Avanafil is metabolized in the liver primarily by the enzyme CYP3A4. Grapefruit juice contains compounds known as furanocoumarins, which inhibit the activity of CYP3A4. As a result, consuming grapefruit juice while taking Avana 100mg can slow down the metabolism of avanafil, leading to higher levels of the medication in the body than intended.
High levels of avanafil in the bloodstream can increase the risk of side effects such as headache, dizziness, low blood pressure, and priapism (a prolonged and painful erection). Therefore, it is generally recommended to avoid consuming grapefruit or grapefruit juice while taking Avana or other medications metabolized by CYP3A4.
If you have any questions or concerns about potential interactions between Avana and grapefruit or grapefruit juice, it's essential to discuss them with your healthcare provider. They can provide personalized advice based on your individual health status and medication regimen.
Avanafil is metabolized in the liver primarily by the enzyme CYP3A4. Grapefruit juice contains compounds known as furanocoumarins, which inhibit the activity of CYP3A4. As a result, consuming grapefruit juice while taking Avana 100mg can slow down the metabolism of avanafil, leading to higher levels of the medication in the body than intended.
High levels of avanafil in the bloodstream can increase the risk of side effects such as headache, dizziness, low blood pressure, and priapism (a prolonged and painful erection). Therefore, it is generally recommended to avoid consuming grapefruit or grapefruit juice while taking Avana or other medications metabolized by CYP3A4.
If you have any questions or concerns about potential interactions between Avana and grapefruit or grapefruit juice, it's essential to discuss them with your healthcare provider. They can provide personalized advice based on your individual health status and medication regimen.